NEJM â Collection Updates for SARS

CLINICAL IMPLICATIONS OF BASIC RESEARCH: A Candidate Vaccine for Severe Acute Respiratory Syndrome

Robert E. Johnston, Ph.D. — Thu, 19Â AugÂ 2004 00:00:00 -05:00

The story of the epidemic of severe acute respiratory syndrome (SARS) is a frightening one in many respects, but it provides heartening news about our ability to respond to an...

ORIGINAL ARTICLE: Public Health Measures to Control the Spread of the Severe Acute Respiratory Syndrome during the Outbreak in Toronto

Thu, 03Â JunÂ 2004 00:00:00 -05:00

Background: Toronto was the site of North America's largest outbreak of the severe acute respiratory syndrome (SARS). An understanding of the patterns of transmission and the effects on public health...

PERSPECTIVE: Planning for Epidemics â The Lessons of SARS

Robert A. Weinstein, M.D. — Thu, 03Â JunÂ 2004 00:00:00 -05:00

In terms of sheer drama, the emergence of the severe acute respiratory syndrome (SARS) rivaled the most exotic Michael Crichton thriller. A novel viral strain spread in âwet marketsâ from...

ORIGINAL ARTICLE: Laboratory-Acquired Severe Acute Respiratory Syndrome

Thu, 22Â AprÂ 2004 00:00:00 -05:00

The outbreak of severe acute respiratory syndrome (SARS) in Singapore ended in late May 2003.1 The Centers for Disease Control and Prevention (CDC) removed its travel alerts for Toronto, Hong...

ORIGINAL ARTICLE: Evidence of Airborne Transmission of the Severe Acute Respiratory Syndrome Virus

Thu, 22Â AprÂ 2004 00:00:00 -05:00

Background: There is uncertainty about the mode of transmission of the severe acute respiratory syndrome (SARS) virus. We analyzed the temporal and spatial distributions of cases in a large community...

PERSPECTIVE: Airborne Transmission of Communicable Infection â The Elusive Pathway

Chad J. Roy, M.S.P.H., Ph.D., and Donald K. Milton, M.D., Dr.P.H. — Thu, 22Â AprÂ 2004 00:00:00 -05:00

What does it mean to describe an infection as having airborne transmission, and what are the clinical implications? There is a fitting symmetry between the report by Yu et al....

CORRESPONDENCE: Estimated Timing of the Last Common Ancestor of the SARS Coronavirus

Fanya Zeng, Ph.D., Ken Y.C. Chow, B.Sc., and Frederick C. Leung, Ph.D. — Thu, 18Â DecÂ 2003 00:00:00 -05:00

To the Editor: Using the viral sequences derived from clinical specimens collected in Hong Kong between February and April 2003 from 139 patients with the severe acute respiratory syndrome (SARS),1...

CORRESPONDENCE: Detection of SARS Coronavirus in Plasma by Real-Time RT-PCR

Thu, 18Â DecÂ 2003 00:00:00 -05:00

To the Editor: The identification and sequencing of a novel coronavirus1 associated with the recently described severe acute respiratory syndrome (SARS)2 have permitted the development of antibody-based and genome-based tests...

REVIEW ARTICLE: The Severe Acute Respiratory Syndrome

Thu, 18Â DecÂ 2003 00:00:00 -05:00

The severe acute respiratory syndrome (SARS) is responsible for the first pandemic of the 21st century. Within months after its emergence in Guangdong Province in mainland China, it had affected...

ORIGINAL ARTICLE: Transmission of the Severe Acute Respiratory Syndrome on Aircraft

Thu, 18Â DecÂ 2003 00:00:00 -05:00

Background: The severe acute respiratory syndrome (SARS) spread rapidly around the world, largely because persons infected with the SARS-associated coronavirus (SARS-CoV) traveled on aircraft to distant cities. Although many infected...

PERSPECTIVE: SARS â One Year Later

Donald E. Low, M.D., and Allison McGeer, M.D. — Thu, 18Â DecÂ 2003 00:00:00 -05:00

It was just over a year ago, in November 2002, that the first case of what was to become known as the severe acute respiratory syndrome (SARS) was identified in...

CORRESPONDENCE: Molecular Epidemiology of SARS â From Amoy Gardens to Taiwan

Rossa W.K. Chiu, M.B., B.S., Stephen S.C. Chim, Ph.D., and Y.M. Dennis Lo, D.M. — Thu, 06Â NovÂ 2003 00:00:00 -05:00

To the Editor: The outbreak of severe acute respiratory syndrome (SARS) in Taiwan described by Hsieh (Aug. 14 issue)1 grew rapidly from mid-April 2003. We note the chronologic relation between...

CORRESPONDENCE: SARS and the Internet

Jeffrey M. Drazen, M.D., and Ying-Hen Hsieh, Ph.D., and Edward W. Campion, M.D. — Thu, 14Â AugÂ 2003 00:00:00 -05:00

To the Editor: Your editorial (May 15 issue)1 describes the speed and power of the Internet in communicating to the world knowledge about severe acute respiratory syndrome (SARS) and the...

CORRESPONDENCE: A Novel Coronavirus and SARS

Qibin Leng, Ph.D. and Zvi Bentwich, M.D. — Thu, 14Â AugÂ 2003 00:00:00 -05:00

To the Editor: Ksiazek et al. (May 15 issue)1 report that there is antibody cross-reactivity between serum from a patient with severe acute respiratory distress syndrome (SARS) and antibodies that...

CORRESPONDENCE: SARS in Hong Kong

Ya Ping Wu, Ph.D., Ran Wei, M.D., and Philip G. de Groot, Ph.D. — Thu, 14Â AugÂ 2003 00:00:00 -05:00

To the Editor: Lee et al. (May 15 issue)1 describe the clinical and laboratory features of 138 cases of suspected severe acute respiratory syndrome (SARS) in Hong Kong. It is...

CORRESPONDENCE: Managing SARS

Thu, 14Â AugÂ 2003 00:00:00 -05:00

To the Editor: With regard to the article by Wenzel and Edmond (May 15 issue),1 the management of suspected cases of severe acute respiratory syndrome (SARS) is not harmless. Recently,...

PERSPECTIVE: SARS â Looking Back over the First 100 Days

Jeffrey M. Drazen, M.D. — Thu, 24Â JulÂ 2003 00:00:00 -05:00

Each winter, a number of surveillance networks are put in place to detect unusual outbreaks of severe respiratory disease. Last winter, although there had been some minor activity, nothing serious...

CORRESPONDENCE: Coronavirus Genomic-Sequence Variations and the Epidemiology of the Severe Acute Respiratory Syndrome

Stephen K.W. Tsui, Ph.D., Stephen S.C. Chim, Ph.D., and Y.M. Dennis Lo, D.M. — Thu, 10Â JulÂ 2003 00:00:00 -05:00

To the Editor: Our teaching hospital was the site of a major outbreak of the severe acute respiratory syndrome (SARS).1 We sequenced viral isolates cultured from clinical specimens from seven...

EDITORIAL: Case Clusters of the Severe Acute Respiratory Syndrome

Jeffrey M. Drazen, M.D. — Thu, 15Â MayÂ 2003 00:00:00 -05:00

Just over three weeks ago, the World Health Organization (WHO) issued a worldwide notice about the severe acute respiratory syndrome (SARS). It described a rapidly progressive, sometimes fatal pneumonia that...

CORRESPONDENCE: SARS in Northern Vietnam

Thu, 15Â MayÂ 2003 00:00:00 -05:00

To the Editor: The outbreak of a new, potentially severe, infectious disease, without known cause or treatment, is a stressful challenge, both for patients and for physicians. Our only therapeutic...

CORRESPONDENCE: The Use of Corticosteroids in SARS

Nelson Lee, M.B., B.S., and Yuji Oba, M.D., and Joseph Sung, M.D. — Thu, 15Â MayÂ 2003 00:00:00 -05:00

To the Editor: The use of systemic corticosteroids in patients with the severe acute respiratory syndrome (SARS) is of serious concern. Lee and colleagues report anecdotal success in their article...

EDITORIAL: Faster . . . but Fast Enough? Responding to the Epidemic of Severe Acute Respiratory Syndrome

Julie Louise Gerberding, M.D., M.P.H. — Thu, 15Â MayÂ 2003 00:00:00 -05:00

Severe acute respiratory syndrome (SARS) was diagnosed in more than 1800 patients in 17 countries (including the United States and Canada) between February 1 and March 31, 2003. During this...

EDITORIAL: SARS, the Internet, and the

Jeffrey M. Drazen, M.D., and Edward W. Campion, M.D. — Thu, 15Â MayÂ 2003 00:00:00 -05:00

On the Ides of March 2003, a physician was in transit from New York to Singapore by way of Germany. In Germany he was hospitalized and quarantined with a respiratory...

IMAGES IN CLINICAL MEDICINE: Radiologic Manifestations of Severe Acute Respiratory Syndrome

Thu, 15Â MayÂ 2003 00:00:00 -05:00

Soon after returning from Hong Kong, a previously healthy 48-year-old man began to have fever, malaise, dyspnea, and a nonproductive cough. His temperature was 38.5Â°C (101.3Â°F), and his arterial oxygen...

ORIGINAL ARTICLE: Identification of Severe Acute Respiratory Syndrome in Canada

Thu, 15Â MayÂ 2003 00:00:00 -05:00

Background: Severe acute respiratory syndrome (SARS) is a condition of unknown cause that has recently been recognized in patients in Asia, North America, and Europe. This report summarizes the initial...

ORIGINAL ARTICLE: A Major Outbreak of Severe Acute Respiratory Syndrome in Hong Kong

Thu, 15Â MayÂ 2003 00:00:00 -05:00

Background: There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. We report the clinical, laboratory, and radiologic features of 138 cases of suspected SARS during a...

ORIGINAL ARTICLE: A Cluster of Cases of Severe Acute Respiratory Syndrome in Hong Kong

Thu, 15Â MayÂ 2003 00:00:00 -05:00

Background: Information on the clinical features of the severe acute respiratory syndrome (SARS) will be of value to physicians caring for patients suspected of having this disorder.

Methods: We abstracted data...

ORIGINAL ARTICLE: Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome

Thu, 15Â MayÂ 2003 00:00:00 -05:00

Background: Abstract

The severe acute respiratory syndrome (SARS) has recently been identified as a new clinical entity. SARS is thought to be caused by an unknown infectious agent.

Methods: Clinical specimens from...

ORIGINAL ARTICLE: A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

Thu, 15Â MayÂ 2003 00:00:00 -05:00

Background: A worldwide outbreak of severe acute respiratory syndrome (SARS) has been associated with exposures originating from a single ill health care worker from Guangdong Province, China. We conducted studies...

PERSPECTIVE: SARS and Carlo Urbani

Thu, 15Â MayÂ 2003 00:00:00 -05:00

On February 28, the Vietnam French Hospital of Hanoi, a private hospital of about 60 beds, contacted the Hanoi office of the World Health Organization (WHO). A patient had presented...

PERSPECTIVE: SARS-Associated Coronavirus

Kathryn V. Holmes, Ph.D. — Thu, 15Â MayÂ 2003 00:00:00 -05:00

The discovery that a novel coronavirus is the probable cause of the newly recognized severe acute respiratory syndrome (SARS), reported by Ksiazek et al. (pages 1953â1966), Drosten et al. (pages...

PERSPECTIVE: Managing SARS amidst Uncertainty

Richard P. Wenzel, M.D., and Michael B. Edmond, M.D., M.P.H. — Thu, 15Â MayÂ 2003 00:00:00 -05:00

In November 2002, a businessman from the city of Foshan in the southern Chinese province of Guangdong may have been the first victim of a mysterious illness called severe acute...

NEJM â Collection Updates for SARS

CLINICAL IMPLICATIONS OF BASIC RESEARCH: A Candidate Vaccine for Severe Acute Respiratory Syndrome

ORIGINAL ARTICLE: Public Health Measures to Control the Spread of the Severe Acute Respiratory Syndrome during the Outbreak in Toronto

PERSPECTIVE: Planning for Epidemics â The Lessons of SARS

ORIGINAL ARTICLE: Laboratory-Acquired Severe Acute Respiratory Syndrome

ORIGINAL ARTICLE: Evidence of Airborne Transmission of the Severe Acute Respiratory Syndrome Virus

PERSPECTIVE: Airborne Transmission of Communicable Infection â The Elusive Pathway

CORRESPONDENCE: Estimated Timing of the Last Common Ancestor of the SARS Coronavirus

CORRESPONDENCE: Detection of SARS Coronavirus in Plasma by Real-Time RT-PCR

REVIEW ARTICLE: The Severe Acute Respiratory Syndrome

ORIGINAL ARTICLE: Transmission of the Severe Acute Respiratory Syndrome on Aircraft

PERSPECTIVE: SARS â One Year Later

CORRESPONDENCE: Molecular Epidemiology of SARS â From Amoy Gardens to Taiwan

CORRESPONDENCE: SARS and the Internet

CORRESPONDENCE: A Novel Coronavirus and SARS

CORRESPONDENCE: SARS in Hong Kong

CORRESPONDENCE: Managing SARS

PERSPECTIVE: SARS â Looking Back over the First 100 Days

CORRESPONDENCE: Coronavirus Genomic-Sequence Variations and the Epidemiology of the Severe Acute Respiratory Syndrome

EDITORIAL: Case Clusters of the Severe Acute Respiratory Syndrome

CORRESPONDENCE: SARS in Northern Vietnam

CORRESPONDENCE: The Use of Corticosteroids in SARS

EDITORIAL: Faster . . . but Fast Enough? Responding to the Epidemic of Severe Acute Respiratory Syndrome

EDITORIAL: SARS, the Internet, and the

IMAGES IN CLINICAL MEDICINE: Radiologic Manifestations of Severe Acute Respiratory Syndrome

ORIGINAL ARTICLE: Identification of Severe Acute Respiratory Syndrome in Canada

ORIGINAL ARTICLE: A Major Outbreak of Severe Acute Respiratory Syndrome in Hong Kong

ORIGINAL ARTICLE: A Cluster of Cases of Severe Acute Respiratory Syndrome in Hong Kong

ORIGINAL ARTICLE: Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome

ORIGINAL ARTICLE: A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

PERSPECTIVE: SARS and Carlo Urbani

PERSPECTIVE: SARS-Associated Coronavirus

PERSPECTIVE: Managing SARS amidst Uncertainty

NEJM â Collection Updates for SARS

PERSPECTIVE: Planning for Epidemics â The Lessons of SARS

PERSPECTIVE: Airborne Transmission of Communicable Infection â The Elusive Pathway

PERSPECTIVE: SARS â One Year Later

CORRESPONDENCE: Molecular Epidemiology of SARS â From Amoy Gardens to Taiwan

PERSPECTIVE: SARS â Looking Back over the First 100 Days